Single-nucleotide polymorphism rs 175080 in the MLH3 gene and its relation to male infertility

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

P-196: Association rs3819392 Single Nucleotide Polymorphism within The KIT Gene with Azoospermic Male Infertility

Background: Recent studies have shown that KIT is expressed in the cytoplasm of the spermatogonia, acrosomal granules and leydig cells. Reduction in KIT expression in oligozoospermia with an increase in the germ cell apoptosis process. Three single-nucleotide polymorphisms (SNPs) have been identified and these have been studied to discover KIT role in the male infertility. The aim of this study...

متن کامل

Single nucleotide polymorphism of the lactoferrin gene and its association with milk production and reproduction traits in Iranian Holstein cattle

Bovine lactoferrin (LTF) is a member of the transferrin family of iron-binding proteins. This protein is present in a wide variety of biological fluids and shows important physiological functions in body. In this study, 404 blood samples were collected from Holstein dairy farms in Iran. A 301 bp fragment of intron 6 in bovine LTF gene was amplified and the animals were genotyped using polymeras...

متن کامل

single nucleotide polymorphism rs 2476601 of ptpn22 gene and susceptibility to rheumatoid arthritis in iranian population

the rs2476601 (r620w, c1858t) polymorphism in ptpn22 gene has been repeatedly reported to be associated with rheumatoid arthritis (ra). the rs 2476601 is widely suggested for predictive testing and risk assessment for ra. the aim of this study was to test the possible association of this snp with ra in iranian population.a total of 872 samples (405 confirmed ra patients and 467 healthy controls...

متن کامل

Single Nucleotide Polymorphisms in a Male Infertility- Related Gene CatSper

Objective To identify single nucleotide polymorphisms (SNPs) of human CatSper gene, the mouse homologous gene product, which plays a crucial role in mouse male sterility. Methods We demonstrated a systematic screening of SNPs in coding regions and flanking intronic regions of human CatSper gene in a sample subset from a total 210 male individuals by DNA sequencing. Then we used PCR single-stran...

متن کامل

new single nucleotide polymorphism g5508a in the sept12 gene may be associated with idiopathic male infertility in iranian men

background: male infertility is a multifactorial disorder, which affects approximately 10% of couples at childbearing age with substantial clinical and social impact. genetic factors are associated with the susceptibility to spermatogenic impairment in humans. recently, sept12 is reported as a critical gene for spermatogenesis. this gene encodes a testis specific member of septin proteins, a fa...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Assisted Reproduction and Genetics

سال: 2015

ISSN: 1058-0468,1573-7330

DOI: 10.1007/s10815-015-0594-z